Various techniques are used for the enhancement of the solubility of poorly soluble drugs which include physical and chemical modifications of drug and other methods like particle size reduction crystal engineering salt formation solid dispersion use of surfactant complexation and so forth. Among various techniques for solubility enhancement physical modifications of drug products such as reducing the particle size and modifying crystal habit are common approaches to increase drug solubility . Nanoparticulate drug delivery highlights and examines the transition of nanoparticulate drug delivery systems from the laboratory into a commercially viable sector the first chapters of the book provide an overview of the use and characterization of nanoparticulate systems as drug carriers including the assessment of their morphology . Drug delivery techniques translating polymer science for drug delivery evolution of novel drug delivery systems that overcome bioavailability and delivery obstacles however despite the growing importance of solubility enhancement low drug solubility and stability often reduce the effectiveness of an. For the past few decades there has been a considerable research interest in the area of oral drug delivery using nanoparticle np delivery systems as carriers oral nps have been used as a physical approach to improve the solubility and the stability of active pharmaceutical ingredients apis in
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